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Re:Enemy within: gut bacteria drive autoimmune disease by jhartmann on Saturday March 10, 2018 @07:14PM (#16560880)
I know of several hackers that have gone through YC have autoimmune conditions, and I would say there is a larger population of people that have autoimmune conditions then our parents generation. I myself have ankylosing spondylitis, and live with chronic pain, back and neck problems. Probably just really interesting to people like us, who want to hack our way out of problems that medicine doesn't have good answers for yet.
Re:Enemy within: gut bacteria drive autoimmune disease by colordrops on Saturday March 10, 2018 @08:54PM (#16561278)
I've got the same thing - my neck and shoulders are wrecked, with two slipped discs and severe degeneration, more than should be for my age. The two things that worked to remove nearly all of my pain:

* Whole 30 anti-inflammation diet

* Mysore-style Ashtanga Yoga

If both are done diligently together every day, after 2 weeks you will likely see drastic improvement.

It's not a cure - if I stop, after 2 days I'm back in excruciating pain. But when I do these regularly, I can go through the day forgetting that I have neck problems.

Re:Enemy within: gut bacteria drive autoimmune disease by halfjoking on Saturday March 10, 2018 @09:20PM (#16561380)
I'm currently on the "low-lectin" diet which seems to be the most extreme of the anti-inflammation diets.

Even though the doctor (Gundry) provides mostly anecdotal evidence in his book The Plant Paradox - you might want to try cutting out cashews and nightshade vegetables which are approved on Whole 30. I felt a difference when I cut those two things out.

Re:Enemy within: gut bacteria drive autoimmune disease by graeme on Saturday March 10, 2018 @11:23PM (#16561684)
Is there any authoritative source on nightshades and inflammation/digestive issues?

After extensive testing, I believe they cause serious issues for me (fatigue, bowel issues, etc)

But when I search for info, I just find sites from sort of woo-woo sources. (Chiropractors, naturopaths, etc)

I'd like to read something more definitive. Both for my own purposes, and also to point people to, as the category itself makes people skeptical.

Spicy food, sure, people get that. But potatoes? That's a weird one for most.

Re:Enemy within: gut bacteria drive autoimmune disease by halfjoking on Sunday March 11, 2018 @12:02AM (#16561776)
Nope. The only studies are in mice/rats. I was disappointed that The Plant Paradox "references" linked to articles on the web like this: https://www.dietvsdisease.org/nightshade-vegetables/
Re:Enemy within: gut bacteria drive autoimmune disease by graeme on Sunday March 11, 2018 @02:57PM (#16564246)
I see. What's your personal view on eliminating them? I'm trying to rule out the possibility that I've given myself a nocebo effect.

(I've had enough cases where I didn't realize something was a nightshade and I had a bad effect from it that I don't think I'm merely fooling myself, but the quality of articles about it is disturbing).

What did the rodent studies find?

Re:Enemy within: gut bacteria drive autoimmune disease by modi15 on Sunday March 11, 2018 @01:38AM (#16561940)
Could you elaborate a little bit on how you got started with Ashtanga Yoga ?

Any book or yogashaala recommendation ?

Re:Enemy within: gut bacteria drive autoimmune disease by colordrops on Sunday March 11, 2018 @03:39AM (#16562073)
A coworker introduced me. I was already looking for a place to practice yoga so when a recommendation came in I latched onto it quickly.
Re:Enemy within: gut bacteria drive autoimmune disease by chiefalchemist on Sunday March 11, 2018 @08:31AM (#16562747)
Ideal book for the Whole 30 diet? Tia
Re:Enemy within: gut bacteria drive autoimmune disease by nerdponx on Saturday March 10, 2018 @07:33PM (#16560954)
I don't think I'd be any kind of "hacker" if it weren't for undiagnosed celiac disease. If I wasn't been too sick to go out and do my normal activities, I never would have sat at home learning to program.

It's incidence also, anecdotally, seems to be increasing.

Re:Enemy within: gut bacteria drive autoimmune disease by borne0 on Saturday March 10, 2018 @10:51PM (#16561610)
Isn't untreated Celiac disease also associated with foggy cognition and poor memory?
Re:Enemy within: gut bacteria drive autoimmune disease by nerdponx on Sunday March 11, 2018 @02:30PM (#16564137)
Yes. That was a bad time in my life.