Re:Ask HN: I'm writing a book about white-collar drug use, i...
by Balgair on Monday February 26, 2018 @05:02PM
(#16469377)
Unfortunately, it seems that B vitamins do not 'synergize' with caffeine in an appreciable way, per an article from the LA times in 2008. Caffeine does have a 'negative' effect on circulating B vitamin percentage, but I could only find one study from 2008 about it, and it's not unhealthy. As is, the B vitamins with coffee really only seem to help in the elderly.
That said, yeah, mate is pretty mild in terms of caffeine content.
http://www.latimes.com/health/la-he-skeptic14-2008jul14-stor...
Drinks such as coffee have a ton of caffeine in comparison. A cup of coffee has around ~200mg of caffeine, while yerba mate drinks have around ~70mg: http://guayaki.com/caffeine_meter.html
So drinking yerba mate is a lot like drinking tea as far as the caffeine experience goes.