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Re:Ask HN: I'm writing a book about white-collar drug use, i... by kelnos on Monday February 26, 2018 @03:44PM (#16468809)
> I remember a CEO of one of my early startups would give me 5mg addies to help me get more done.

Jesus. If that happened to me, my first stop would be to the board/investors to report it, and my second would be out the door and to a new job.

> It's only way to do some of the things that the really successful engineers are doing. You forgo eating, exercise, etc... and spend 110% of your time on working and chasing the high of getting shit done.

I suspect your belief of the effectiveness here is quite a large exaggeration. You might have tunnel-vision focus and the ability to stay awake for long stretches and work, but the quality of that work just cannot be top notch. If you don't eat, exercise, or sleep much, your brain is not getting the fuel it needs to work properly, and no drug can replace or mimic that. Over the (very) short term you'll see a benefit, but after that it's just vapor.

Re:Ask HN: I'm writing a book about white-collar drug use, i... by ergothus on Monday February 26, 2018 @06:55PM (#16470060)
I won't advocate the abuse of any particular drug, but I will say it's not as simple as trading quality for focus. There is a margin of overhead that comes with poor focus, so sharpening can lead to improved productivity without loss of quality. To a point, after which your comment applies.

I'm saying this not to say "Actually..." but so that no one discounts your valid point just because they have some anecdote where it didn't apply. There is a point where you pay (or at least stop winning), and our understanding of where that point is and how stable it is is very lacking. Likewise, our judgement under the influence of something should not be considered 100% reliable. Neither should our judgement NOT under the influence, but people tend to become zealots when defensive, and fewer people are defensive of being "normal".

I had a friend that I was discussing nootropics with - It's a topic I'm very interested in, but I'm not interested in any notable experimentation because, well, I've only got one brain and our understanding of it is pathetic. His answer was that by experimentation you'd discover what worked. We were definitely coming at it from opposite ends despite similar interests.

Re:Ask HN: I'm writing a book about white-collar drug use, i... by 3pt14159 on Monday February 26, 2018 @07:32PM (#16470213)
Anecdotal, I know, but I've heard of this at two companies. One of which jokingly put them in Pez dispensers.