Re:Many medical devices on the market have undergone no clin...
by tinokid on Thursday February 15, 2018 @09:30PM
(#16389445)
Does diminishing returns/low hanging fruit mean anything to you?
Also, from that pool of drugs you're referring to, we've eliminated a number of things that had strong effects but whose side-effects were later found after careful study to not outweigh the benefits.
There is a similar effect from carefully studying devices/surgical interventions--not so much a raft of "new innovations" but rather the culling of a lot of things that were overused or actually harmful. Huge cost savings, big improvements in population health & lots of gored oxen.
Why? New drugs have been getting less effective over time, even though the scientific requirements to get them approved have been becoming stricter. The majority of our most effective drugs were approved before there were any requirements for demonstrating safety and/or efficacy.