Some RV makers (both commercial [0] and DIY [1]) are already on 48V systems for their house batteries. Advantages: lighter wiring, can use a higher-voltage alternator that needs less heat dissipation. Note that the system in the Sprinter van is able to run the air conditioner at 100% duty for 8 hours, then allow the alternator to recharge the battery while continuing to run the A/C unit. Which is really impressive (and should be, for the $200k their RVs cost)

[0] https://www.youtube.com/watch?v=ofCcnxJxzeE

[1] https://www.youtube.com/watch?v=LV8fyzOTjsk