Take it up with BeOS? :D
Hah, I think icons are the place isometric views work really well, actually! Lots of room for highly differentiated objects with an isometric view. However, text and interconnections and maps are really not great at these isometric angles. And I do really like the icons used in the figure in the original post, just not the whole.
I think that Tufte needs to make a resurgence with this generation of designers.