>> None of your criticisms from wikipedia pertain to this publication. The paragraph is essentially making the argument that a randomized, double blind (DB), placebo controlled (PC) clinical trial (RCT) is unlikely to show that curcurmin is effective. yet, the published article is exactly that, and shows a statistically measurable impact on a clinically meaningful endpoint: a direct refutation of the paragraph.

I think, if there are solid reasons to believe that studies on curcumin will not turn up any useful results and then a study finds results it calls significant, the chances are that either that study is not designed very well, or its results are not significant, despite the claims of the authors.

Apologies in advance for the controversial example, but this reminds me of the controversy about Daryl Bem's parapsychology research a few years ago- the author claimed his study was methodologically unassailable, but of course he was making an absurd claim (essentially, that people can receive information from the future via ESP).

Edit: removed cruft.