I would think best to split up amongst a few at least, I like to aim for coins with a definite real world use, and avoid POW coins as I think their days are numbered.

Hard not to like Stellar Lumens with the IBM connection, working tech and real world use already happening.

Universa issues today, it seems they aim to take on Mastercard and Visa, if true worth a punt in my opinion.

TEL aims to internationalise the MPesa branchless banking system which works via mobile phone - there are 1.5B bank accounts and 5B phones in the world, the gap is the potential.

Disclaimer: I have been wrong many times before.

if you are going to invest $1000 then diversify across a bunch of coins in which you understand (or can pretend to understand) the technology and potential use cases. Then after purchasing and storing them securely forget about them and set yourself a reminder to check them in November.

If you want to make a "mutual fund" so to speak I would suggest looking at the top 25 by market cap and investing some in each one. Keep in mind the top 25 by cap will change every so often so I would check back every month and re-allocate.