You haven't seen the current JS ecosystem, have you?

Now if you opt to ignore the entire modern JS scene - all that Babel, Webpack, NPM stuff - and just write plain old JS in a text editor to execute directly, then yes. And with browser dev tools having a half-decent REPL, I'd say this is a pretty good way to introduce someone to programming. Browsers have powerful features for UI and graphics built in, so even the "hello world" programs won't be boring.

(Also: technically, there is something to set up; you won't be able to run everything through file:// because $security, so you need a minimal local HTTP server to serve your files for you.)