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Re:Do You Have the Right to Plead Not Guilty When Your Lawye... by da_chicken on Wednesday January 17, 2018 @11:20AM (#16169114)
There are cases of body integrity identity disorder (https://en.wikipedia.org/wiki/Body_integrity_identity_disord...) being treated by amputation. It's a rare condition, but the discussion about the ethics of voluntary amputation as treatment is quite extensive:

https://www.ncbi.nlm.nih.gov/pubmed/15948330 https://www.ncbi.nlm.nih.gov/pubmed/19132621 https://www.ncbi.nlm.nih.gov/pubmed/17115518

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