I remember something marketed as a “hypercomputer” by Starburst Systems or something like that (long since defunct, apparently... I'm referring back to the late 1990s and early 2000s) that “compiled software to hardware” by substituting parallel CPUs with FPGAs.
This approach has been tried - as it turns out, we're not very good at writing compilers.
Course, in the context of the larger thread, I can't help but wonder how much more attack surface this would tend to create.