I dont think you know what .NET is - it's an entire software platform comprising of several languages (C#,F#,VB) along with a compiler toolchain (Roslyn,RyuJIT), managed runtime (CLR), high quality standard libraries (.NET standard/BCL), and productive application frameworks (ASP.NET), that compile into programs that can now run on Windows, Mac, Linux, mobile phones and even Raspberry Pi's.

These programs can do anything, just like any other code in any other language, and the protocols (like HTTP or UDP) to talk between processes or programs have nothing to do with the code itself, which gets compiled down to the same machine level instructions anyway regardless of what language you use.