I think the reinvigorating the opposition thing already happened when Obama was elected. That is how we got the Tea Party and how we got Trump. The Democratic party that Clinton ran under wasn't that different than the party of her husband. The Republican Party of Trump is drastically different than the party of GW Bush.
I'm not quite sure if that was true if Clinton had one, we'll never know, but one thing is for certain: The opposition to the current government and policies seems reinvigorated, and the generational aspect of it could be true as well. Perhaps this country really did need an enema.