Interesting. I'm running Debian unstable, and recently my system would sometimes lock up under heavy memory pressure. I'm using VirtualBox, which has its own kernel module, so I can't be sure Linux itself is to blame, but the timing seems to coincide with when I switched to that kernel version. Maybe transparent hugepages uncovered a VirtualBox bug or even a kernel bug. And I care about worst case performance more than average performance, so I just now set it to "never".