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A comment on Faecal transplant effectively treats recurrent or unresponsive Clostridium diff. Parent comment

Re:Faecal transplant effectively treats recurrent or unrespo... by astura on Friday November 24, 2017 @11:06AM (#15771516)
Placebo controlled trials for C Diff would be unethical thus would likely not be legal in any country that conduct their trials with any ethical standards. Just like you wouldn't have a placebo group in a trial for an new AIDS or cancer treatment. In this case we're looking for a treatment that works just as well or better than current treatments.
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Re:Faecal transplant effectively treats recurrent or unrespo... by cpncrunch on Friday November 24, 2017 @11:49AM (#15771729)
Well clearly that's not true because placebo controlled trials into FMT for c.diff have been done in the USA. AIDS and cancer have objective measures, whereas with c.diff the trials just look at subjective measures.

Also, given that the placebo improvement rates are 40-90% in all c.diff trials, it would be unethical to not use a placebo arm.

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