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Re:Sugar industry withheld possible evidence of cancer link ... by simcop2387 on Wednesday November 22, 2017 @03:28PM (#15760303)
At least with erythritol some people have bad reactions to it. Nothing life threatening as far as I know, but it can give me very bad gas, and for one other person I know it's like eating Olestra Chips[1]. That said there are other sweeteners that don't seem to have that effect but they don't seem to behave quite as closely to sugar in cooking as erythritol does.

[1] https://en.wikipedia.org/wiki/Olestra#Side_effects

Re:Sugar industry withheld possible evidence of cancer link ... by didgeoridoo on Wednesday November 22, 2017 @03:36PM (#15760371)
Most sugar substitutes are indigestible by humans, but readily metabolized by gut bacteria. This can result in a "Satan's Diarrhea Hatebears" scenario [0], especially when suddenly consumed in large amounts.

[0]: https://www.amazon.com/ss/customer-reviews/B00DE4GWWY

Re:Sugar industry withheld possible evidence of cancer link ... by pmoriarty on Wednesday November 22, 2017 @03:41PM (#15760412)
Tagatose has become my go-to sugar substitute. It is indistinguishable from sugar for me. There's an interesting article in Wired about its discovery and properties here:

https://www.wired.com/2003/11/newsugar/