> the actors behind the cartoon are reading a script written by someone...

So.. it really doesn't matter who teaches and who listens, because ultimately they're both actors reading from a script. How does that play in favor of your argument?

Not to mention the woman he's explaining to is a scientist researcher, and at the end of the video, they have Dr. Azra Raza as a guest (who is also a woman) to further solidify the arguments.

If you think you're defending anything by calling it "mansplaining" and complaining that women aren't treated fairly, you're wrong and you're not helping anyone.

the cartoon depicts an incompetent woman scientist being talked-down to by an arrogant dick! It has the form:

woman: "<erroneously> science says X"

man : "<correcting her> actually the truth is Y"

The jerk also talks-down to us the audience. It's terrible science-education and it's not "humor"

Would it be any better if the genders of the actors were reversed?

"mansplain" is a gender-biased criticism of behavior. It implies that the gender of the participants is the problem, rather than the attitudes or behavior.

But apparently the mice in the study react to the gender, so maybe it's germane...

everyone know's it's men who do it so don't pretend it's a reversible situation

Sorry, I mistook you for someone attempting to add value to the conversation.