News for hackers. Stuff that matters.

A comment on CRISPR Can Now Edit Genes Using Nanoparticles Instead of Viruses.

Re:CRISPR Can Now Edit Genes Using Nanoparticles Instead of ... by lukeschlather on Sunday November 19, 2017 @11:33AM (#15734512)
From the paper, it sounds like the particle they constructed is about 120nm in diameter. So a bit larger than the viruses previously used. Which are also nanoparticles, so I guess it's more that this delivery system isn't based on a virus.

I guess, one thing I don't quite understand: are the viruses used in CRISPR really viruses (can they self-replicate using the cells they alter?) Or are they just nanomachines based on viruses?

[ Parent | on HN ]
Re:CRISPR Can Now Edit Genes Using Nanoparticles Instead of ... by 88e282102ae2e5b on Sunday November 19, 2017 @11:38AM (#15734536)
The viruses used to deliver CRISPR in the past are not able to replicate. They're so small that you have to remove all of the viral DNA in order to even fit your CRISPR-coding genes inside.
[ Parent | on HN ]