So you're saying we should all just settle for Javascript, Python, Java, and C because they're familiar and not esoteric (whatever that means)? Should we not consider ReasonML an option for frontend development, even though it solves many problems, because it is esoteric?

The problems you list above are true enough regardless of language choice. I've seen disasters in Clojure as many times as I've seen disasters in Java or Python. Also, why are first-time Clojure programmers code worse than first-time C programmers?