A lot of artifacts are easier to deal with on a hexagon-pixel grid. Halftoning and error-diffusion dithering work really well.
I'd guess that the need for error diffusion and half-toning might wane in the future. (Not sure about that, but that's what I'd guess.) Are there other benefits you get with hex images?
The downside is that there are a zillion implementations of everything you can imagine w/r/t a square grid, whereas implementations on a triangular grid of hexagonal pixels are fewer and further between, often some crappy matlab code written by a grad student, so you’d maybe need to reimplement, optimize, debug, etc. a whole pile of tools, or even invent some new algorithms for doing stuff that hasn’t been tried on such a grid before.
There have been lots of papers written about the topic, and at least one book. http://www.springer.com/us/book/9781852339142
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It’s similar to the advantages you get from tri-axial fabric: it’s better but requires custom machinery, so in practice is only used for bullet-proof stuff, space suits, and art projects. Hexagonal pixels end up getting used in medical imaging, astronomical imaging, and the like, where pixels are individually expensive.
http://www.redblobgames.com/grids/hexagons/
It's written with game design in mind, but many of the techniques are useful just the same.
Lots, if you're into printing. Banding that's invisible on a monitor can become a monster when printed. An expensive monster mistake if you're printing a poster sized giclee.
This is a big reason why Photoshop dithers by default when going from a higher range down to 8 bits per channel.
Another reason the need for dither might be even increasing today is that digital cameras have only very recently gotten better than an 8 bit signal to noise ratio. We've had 16 bit RAW formats for a long time, but most cameras still had noise that was greater than 1/256. I tested one of my old Canon EOS cameras and found even in very well lit conditions, it's signal was a little over 5 bits, even though I could get a 16 bit image file out.
With the newest cameras, the signal to noise is sometimes exceeding 12 stops, so photographers might be running into banding issues in RAW images more often. Except a lot of them never notice because Photoshop quietly handles it.