If by "dereguation" you mean creating government agencies like Freddie Mac and Fannie Mae, which sole purpose was dissorting mortgage market by allowing banks to offset risk from subprime loans, then yes, last crysis was caused by deregulation :) And of course road to hell is paved with good intentions: government was only trying to make houses more affordable to even the poorest Americans.

And even without such special-purpose institutions government can cause market bubbles by nothing more than its "monetary policy" and artificially induced inflation.