Certainly. To go a little further I would hope that it's not something coopted to salve one's situation, but rather to gain clarity on what your issue might be exactly, and what you might do to resolve it -- whether that means altering the arrangement of your time, or finding a new job, starting a family, going back to school, picking up a new hobby, or quitting everything and joining a monastery.
It can be useful to "quiet the mind", and observe what you are actually thinking and feeling. Sometimes the noise of day-to-day living can be all-consuming -- enter some platitudes about "life passing you by".
I agree with the danger of applying it as if it's that you just have to temper your desires and placate yourself, while thinking that it's only some sort of neuroticism that is causing any suffering in the situation.
I accomplish a shitload of stuff and I don't microdose (I don't even drink coffee). I think of the American work culture as having a horrible sickness where a person's worth is measured only by their output. We are supposed to be constantly producing, never stopping to think if we're even producing the right things.
Sure, maybe some people want to be working all the time. More power to them. However my guess is a lot of people are sucked into it because of the culture and naturally would like a little more free time to themselves.
I think that albert hoffman would be a little aghast at how LSD has been coopted so that it lets you work even harder, though. Certainly Huxley would be.
Using a chemical that, at best, has real theraputic potential and can provide meaningful insight into the world this way just seems tawdry to me.