News for hackers. Stuff that matters.
Re:Combined overconsumption of fat and sugar leads to hypoth... by biomcgary on Tuesday September 05, 2017 @06:42PM (#15179692)
The authors did test the combination. HC or HF alone leads to less inflammation than HCHF. Note that the control diet for all of the experiments is chow, which is HCLF.
Re:Combined overconsumption of fat and sugar leads to hypoth... by chrischen on Tuesday September 05, 2017 @07:21PM (#15179889)
Hmm it’s odd. They did feed them chow, but the chow diet was significantly fewer calories than the HCHF or LCHF diets so it can’t really be compared with them. In fact they didn’t control for calorie intake so for all it’s known the higher calorie consumption of HCHF could be the cause.

According to the results section they also did not evaluate the hyperthalmic microglial activities of the Chow (HCLF) diet so it’s unknown from the paper if If the high carb only diet had detrimental results.

Wish I could ask the authors about these holes.

Re:Combined overconsumption of fat and sugar leads to hypoth... by biomcgary on Tuesday September 05, 2017 @07:50PM (#15180034)
I agree with your concerns. I am also concerned that the chow diet (HCLF) does not provide the same type of carbs (wheat and corn) as the other diets tested (sucrose or starch).