You are issuing a false equivalency here. The opioid epidemic is largely catalyzed by the fact that prescription rates are boosted because doctors are incentivized with money. Furthermore, opiates carry a physical dependency after long enough, creating a positive feedback loop. As a third point, the prescriptions are usually issued for those who are under intolerable pain and so the path to addiction is somewhat smoothed by the fact that they simply need to take that much of the drug to feel human again. Before you know it, you're hooked.

Psilocybin suffers none of these problems. It would be more intellectually honest to compare it to something like marijuana and its uptake in society.