Local restaurants that have been open for decades have been struggling over the past few years in my area (east side of Indianapolis). From talking to one owner, meat prices in particular took a dramatic jump ~5 years ago, but I don't know how accurate/relevant that is.

One was bought, moved, and closed a few months later. Another eliminated dinner. A third, open 24x7 for 40+ years, reduced their hours and then closed entirely, although that appears to be as much poor management as anything.

Quite depressing. I like supporting local restaurants, but painful to get attached to something that's likely going to die.