Affinity Photo is excellent. It's a way yet from parity with Photoshop, but is certainly competitive. And it's subscription free!

If you're into vector illustration, Affinity Designer is a straight replacement for Adobe Illustrator.

Also consider awesome software such as Studio Artist (https://synthetik.com/), and Escape Motions offerings (https://www.escapemotions.com/).

Any conscientious artist should evaluate and consider these alternatives, if only to break up the industry's idiotic enslavement to Adobe.