I'm assuming it's the same as wanting to listen to ABC Melbourne when you live in Sydney - but that means missing out on the local news or particular presenters.
So there are places where the local station carries almost no NPR content.
After asking the question I thought about it more and I think I just need to fully commit to podcasts. I've pretty much stopped watching live TV (except for sports) and the same should probably be true for radio.
You might be able to say "Alexa, play KGOU" (or whatever station you want).
We connected it to our light dimmer and ceiling fan and it was harder than it should be to make it work. We would say "Alexa, turn the lights on" and it would reply with something like "I don't know about a device named lights". So, the natural next question is "Alexa, what devices do you know about?" That should work, but it doesn't.
In a quiet room, the microphones are amazing. But as soon as I turn on the fan over our stove, the white noise makes the Echo practically deaf.
Other things like turning on drop-in was an exercise in frustration. Why can't I just say "Alexa, turn on drop-in for the household?" Instead I had to go to the app, give it access to my contacts, turn on drop in on our contact card, then turn on drop in on both devices.
Frankly, I don't think there should even be a phone app. Go all in on the voice interface.