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Re:Marko – An isomorphic UI framework similar to Vue by stuaxo on Sunday August 20, 2017 @09:35AM (#15058352)
It's great that Qt works with virtualenv and pip, Wx does too.

This is a quite recent phenomenon and to be applauded.

Minus sides -

Neither of these work with pypy yet (ideally the bindings would be rewritten using cffi for best benefit).

The downloads on these are quite big, but maybe this isn't the end of the world.

Gtk still doesn't work with pip like that yet.

Pyimgui may be worth a look if you want a small download that works everywhere, though it does look like it's own thing.

Re:Marko – An isomorphic UI framework similar to Vue by wruza on Sunday August 20, 2017 @10:07AM (#15058446)
Our node_modules are 100Mb too, not counting a browser itself. Gtk recently quit building for MSW at all and relies on MSYS2, and it works now via 'gi', like any gir-enabled libraries, no custom wrappers needed. I ran complex Gtk3 Windows widget galleries last month, for Lua and Python at least.