> As the years go on, loneliness and despair will set in. Those first colonists will likely spend the rest of their lives pretty much with who they landed with. Their lives won't change much at all over the decades they're there,...

They may suffer from an acute version of what is known as prairie madness[1], which American colonists suffered from in the nineteenth century.

> ...and they'll have no hope for things to ever be different.

They will have hope : to go back to Earth.

1. https://en.wikipedia.org/wiki/Prairie_madness