There is also some question whether some things we don't consider intersex are actually a form of intersex, such as homosexuality. A lot points to homosexuality being innate, not learned, and I personally think this points to it being a form of intersex that affects the brain, not the genitals.
Some disorders can cause both. For example, females with Congenital adrenal hyperplasia (CAH) can have ambiguous genitals and also are more likely to be lesbian.
I think she refers that gender is not binary as you can be straight male, straight female, gay male, gay female, bisexual, asexual, etc.
I am not completely sure but I think there can be mutations where you have 2 chromosomes X and 1 Y. So XXY [1]
I think the point she's making is that while men and women have different interests as groups, there are plenty of women who are interested in what are perceived as masculine things (in this case probably computer programming) and vice versa.
I've been doing some reading on transgender individuals, and the current knowledge is that gender identity has some kind of durable biological basis, we just don't know quite what it is yet. It's not simply a delusion and a refusal to accept your "real biological gender" based on your chromosomes, etc. Some people don't identify as either gender.
And like the other poster mentioned, there are genetic outliers like XXY chromosomes (intersex), and other things that can happen such as Androgen Insensitivity Syndrome (XY females due to lack of response to testosterone).
This is similar to the divide I've seen in the media. I have not read the memo in it's entirety, but since the impression I got from reading a few news stories was that Damore had only made his controversial statements in regard to the population, not skill of programmers, I'm curious what causes this disagreement.
I also wonder why Edith felt the need to mention gender not being binary in a discussion partly about whether biological sex influences choice of job, considering that as far as I know biological sex is indeed binary, you either have at least one Y chromosome or you don't. (I'm not a biology nerd so feel free to correct me on this.)