I bet it will fail as Talos 1 did, for the same reason: way too expensive for what it is, for the concerned/hobbyist audience, leaving it for a tiny part of the professional audience... which is not ready either to put their trust in an unreliable project and prefers safe bets.
Compared to the RISC based propietary Unix workstations of 20 years ago, the price is really good.
At work, our CAD people have machines that are in the € 1,000 - € 1,500 price range. Those machines are fairly big and powerful, at least compared to our regular desktop PCs.
It is possible to spend more money on a workstation, if one wants or needs to, and get a more powerful machine. Far more.
Depending on your use case, our CAD machines might be lightweights. But the amount of computing power you can get for € 1,000-1,500 these days is insane compared to the landscape 20 or even 10 years ago.
I am certain the Talos II offers good performance for its price. My point was that I would like to have a machine that comes without any opaque blobs or "management engine", but I am not going to spend that much money on it. I'd be happy go get such a machine in the € 500-1,000 price range at correspondingly lower performance.
Even a bare bones motherboard costs more than $2,000.
I have no doubt this an awesome machine, but that price puts it outside my budget range. :(