Great post with some really great points in the comments as well. There are a TON of upstarts in this space and some already target the areas you've mentioned. Of particular note is Startup Digest (www.thestartupdigest.com), which already has thousands of subscribers and an established presence in tons of cities. At the moment, they send out a weekly newsletter with startup events in each city. Definitely worth subscribing to if you're an entrepreneur.