I think it is true- but specifically when we limit happiness to very low forms of it (cheesecake, casual sex, meaningless gratifications, etc.)
That's not a small point - it's very true when we're talking about that, and I believe it is the type of happiness that is pursued with the most energy, most of the time.
However - if we re-frame happiness to some other definition, say the happiness one finds in keeping a home sanitary, or helping a friend, or building something useful, then I think it has the opposite effect. e.g. the happiness that comes from learning something new that improves the lives of you and those around you, is not the same as that which comes from getting drunk. Pursuing the first will not lead to sadness, but pursuing the latter will.
Apart from Karma-based approach in Gita, you can also look towards the Service-based approach in Sikhism or the Non-Detachment in Buddhism. In Sikhism, service is an integral part of religion and every Sikh is expected to give at least some time to do voluntary service in Gurudwaras(Sikh Temples). This is mostly in the form of chores like cooking food, washing utensils, polishing the shoes of visitors etc. In India, you can find some of the richest Sikhs doing these chores in Gurudwaras.
Similarly in Buddhism, detachment of the self is an important aspect of living a life which involves restraining oneself, cultivating discipline and practicing mindfulness and meditation.
None of them have any details about pursuing happiness specifically.