I've found web-mode to be superior for JSX and ES6 stuff, though I tried to use Yegge's for a while. Though I don't do much JS development anymore, this is my current config for web-mode, though I had Flycheck and Flow types working at one point, as well.
https://gist.github.com/asummers/b8304b8ea78fc331b8177ff35d0...
There are modes for javascript (yegge's js2-mode is one of the more feature rich modes I have seen for any language), angular, and typescript. I have not tried eslint but a quick search for emacs eslint turned up some packages.
What in particular would you be looking for in terms of front-end development?
One issue I run into is problems with poor (auto)indentation when I am editing a file which contains html formatted as a string. For example an html template in an angular module. Anybody have/fix this issue?