Certain breeds of dog get hip dysplasia. Dalmations go deaf. Molosser breeds often have respiratory issues, particularly pugs. This has not stopped people from breeding dogs.

Natural selection will be out the window. It will be replaced entirely by intentional selection. We will certainly see new diseases rooted in human vanity and hubris, and they will become business opportunities for surgeons and pharmacists, just as our natural and lifestyle ailments have become moneymaking industries.

So the great-grandchildren of people that were gifted by their parents with then-fashionable gene mutations will have all new reasons to pay for health care.

And Sylvester McMonkey McBean simply unveils his star-off machine.