I'm young and healthy so that wasn't an issue for me. I have looked at everything from starting shooting ranges to specialty chemical companies. Most regulations are local. Just look at your local zoning and building codes. It's probably 500+ pages. The other main ones are dealing with taxes. "Straightforward" ventures like algotrading suddenly become not worth it when you realize you will spend more time writing code to ensure that all of your transactions are meticulously recorded than you will actually analyzing data and writing trading algorithms. Not to mention you probably need a team of accountants for the million+ trades that can happen in a year. Without a specific industry I can't really explain the regulations as each has their own. I'll try to come back later and explain more but I'm pretty busy today