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Re:Backblaze B2, Cloud Storage on a Budget: One Year Later by cweagans on Wednesday June 28, 2017 @10:38AM (#14654492)
Duplicity supports B2: http://duplicity.nongnu.org/
Re:Backblaze B2, Cloud Storage on a Budget: One Year Later by iofiiiiiiiii on Thursday June 29, 2017 @04:58AM (#14661736)
I use duplicity+B2 for all my personal backups and it works just great. Large VM images? Hundreds of thousands of small files? It can handle it all and do so while maxing out my 100 Mbps connection.

Awesome product!