- No life or ecosystems to disrupt; Mars would be ours to build on, dig up, pollute, irradiate, etc. without wiping out any native species. The only thing to spoil would be the views and landscapes, but we'd be the only ones able to appreciate them anyway.
- Not being stuck on this rock. Mars and the Moon are first steps. In a few centuries, maybe the clouds of Venus, tunnels on Mercury, etc. would be viable. Such colonies aren't "backups" in case of disaster on Earth, any more than people live in Europe as a backup in case of disaster in Africa.
Antarctica doesn't fulfil any of my reasons to live on Mars. In fact, Antarctica is the only place on Earth we've agreed to avoid exploiting! If anything, colonising Antarctica would be a backwards move.
You can't manufacture fuel in orbit (it's a vacuum), and you can't manufacture fuel on the Moon (oxygen can be extracted with a lot of heat, but we can't make rockets without a fuel).
But you can manufacture fuel with Martian atmospheric CO2 and frozen water.