I've seen a few Ophthalmologists, official diagnosis is Blepharitis but ultimately my eyes are constantly tired, floaters, sharp pains, dry from the moment I wake up and have nearly constant muscle spasms.

I've tried fish oil, antibiotics, Restasis, numerous drops and gels, various apps, changing behavior etc. I haven't found the silver bullet but I give my eye lids massages and try to drink plenty of water and try to avoid environments that make it worse. I limit computer use to work hours only and am in a role where I only really use a computer for ~4 hours a day. The last few years things haven't gotten worse but haven't gotten better either.

Best advice I can give is take breaks and have hobbies that don't require a computer.