If you're playing KSP, you can tame the stuttering with the MemGraph[0] mod. I don't know about other Unity-based games (nor do I even know of any other games that suffer from the issue). Also in my case they weren't microstutters, rather ~1-3 second pauses.

[0]http://forum.kerbalspaceprogram.com/index.php?/topic/139128-...