I'm very interested in the possibility of using a WASM VM as a unit of process isolation in an operating system. I actually kind of like Babel-compiled JavaScript, so I'm not as interested in WASM as a way to "get away from JavaScript", but the VM-based containerization possibilities (maybe with hardware-assist) are very cool.

Looks like Docker/Unikernel Systems actually has plans to build something like this: https://github.com/linuxkit/linuxkit/tree/master/projects/mi...