If I could pick what platform I run on, it'd be hardware (and I hope such hardware eventually comes along).
"Cattle, not pets."
(I do realize the pretty horrific undertones of this discussion.)
There is some research going on in using spintronics for neural network, and I think that both density and power usage would be a fraction of a biological system.
There is probably a long way until we can emulate human brains, but for generic neutral networks, I think electronics or spintronics is the probable route.
EDIT:And technically brains are general computing devices. Just really inefficient ones. Emulating logic in wetware is highly inefficient (and usually requires an external memory device, like pen and paper, though pure wetware memory also works in some especially skilled individuals, although still with severe capacity limitations). Of course, emulating wetware in logic isn't terribly efficient, either.
It would be kind of crazy if we develop full AI by literally using brains in vats. But it makes sense (even if it is horrifying). Meat is cheap, and the brain is like an exa-OPS computer running on 20 Watts of power. If you could solve the interface problem and figure out how to actually use it practically, brain is like 6 or 7 orders of magnitude cheaper than the next-cheapest computing substrate. That's like half a century of Moore's Law (and Moore's Law is basically over now... much slower pace, at least).
(Here's an example using rat neurons: https://singularityhub.com/2010/10/06/videos-of-robot-contro... And this one: https://www.newscientist.com/article/dn6573-brain-cells-in-a... )