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Re:LSD microdoses make people feel sharper, and scientists w... by andy_ppp on Monday April 24, 2017 @12:05PM (#14185393)
The point of science is to prove things and refine them correctly; this hacker news comment is not conclusive proof that some small amount of alcohol is a net positive, let alone microdosing LSD. Contrary to your very clear positive statement, microdosing is totally unknown if it works at all.

These systems are incredibly complicated to prove anything in and we are so much more suggestible than we feel we are.

We can't even agree on what LSD should be increasing with microdosing, is it IQ, coding ability or concentration?

Re:LSD microdoses make people feel sharper, and scientists w... by amorphous_hn on Monday April 24, 2017 @02:11PM (#14186570)
Hey, I don't have any real evidence to add, but I would often read articles about LSD microdosing and assumed it was bullshit.

After trying it on myself 5-10ug / day for 6+ months, I think it's been incredibly beneficial.

The crux of it is that if you drop a full tab and pay attention, you'll notice LSD is extremely stimulating - far more than psilocybin. It has a very high level of dopamine receptor activation, which is why even 10 hours into a trip I would notice how different the quality of my attention was - in essence, it was far easier to simply be aware of what was going on.

(Note I have adhd-pi so that's part of why I think microdosing works for me)

In short, a microdose gives the dopaminergic stimulatory benefits, without being overwhelmingly twitchy. It produces a less linear style of thinking than amphetamines (adderall/vyvanse/desoxyn), but still increases general energy, focus, quality of attention etc. Colors feel a tiny bit sharper, visual acuity feels slightly enhanced, physical body control is significantly enhanced (I have far better posture and general neuromuscular control).

Obviously this isn't rigorous evidence, but hopefully it gives a general idea of why one would microdose.

One final thing - 25ug or even 15ug is far too much. IMO 10ug is the upper limit of what would be considered a microdose. My preference is 4-8 ug (obviously dosed as liquid)

Re:LSD microdoses make people feel sharper, and scientists w... by sametmax on Monday April 24, 2017 @12:37PM (#14185692)
Right. This is why it needs more investigation, not rejection, isn't it ?