I don't believe that. Al Capone was notorious for bribing the police and the judges, or intimidating them and their families if bribery failed, to the point where many people thought he was invincible. That turned out to be incorrect:
https://en.wikipedia.org/wiki/Untouchables_(law_enforcement)
There exist people in the world with strong moral standards and fearless attitudes. We just need to identify them and put them in the right positions.
Such an approach hinges on the presumption that the people doing the identifying and appointing are also virtuous and non-corruptible. Any attempt at a guarantee of the neutrality of the arbiters and enforcers will quickly descend into a Seussian "who's watching the watch watchers?" scenario.
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On a tangent, I don't believe regulation-free markets are even possible; power and money are inherently connected (money itself being a form of power), so you'll always have "money in politics", and if governments were to suddenly disappear, then private actors with money would start performing their functions.
No system of regulations you build won't eventually be corrupted because (exactly as he says) there exists no neutral desireless arbiters in our world to enforce them.
No system of regulations you build WON'T get you back here eventually. [0]
[0] https://youtube.com/watch?v=2It2HRGGtCk