I do. I'm only using it with about 7 mailboxes, none of which are terribly huge. It frequently stalls for an entire minute or two, has bizarre behavior and interactions with gmail when I'm writing long emails which gunk up conversations, configuration of mailboxes and SMTP servers are fractured all over the place, and search is only slightly more useless than reddit's search.

Based on some chatter here recently, I just recently switched to trying out Claw, it hasn't been too long yet, so I don't know all of the issues yet, but at least it was easy to setup and is really really snappy and uses about 1/3 of the RAM.