> I think people that follow a lot of accounts must use lists or something else.
What I have done is use Twitter as a real time newsfeed, and do not read all the tweets I missed. I open twitter and look at the current tweets, possibly scrolling back a few hours. If I missed something, who cares. If it was important it will likely show up here or some other aggregating new site I frequent.
Twitter is also great for real-time reactions when watching an event on TV. It's akin to people watching the Super Bowl for the commercials. For some shows, the tweets are better than the show and offer an additional level of entertainment.
For me I follow about 30 ppl and remove the too talkative ones inorder for the feed to stay manageable and provide the right amount of signal. That's about 10-20 tweets/day. I think people that follow a lot of accounts must use lists or something else.