With the numbers I tend to play with, if it's enough to live off the interest comfortably for the rest of my life, sure. Then I can work on whatever I want with my time rather than avoiding projects because of the assumed inattention they would receive.

If the company has more potential than the offer, most likely no.

The real question is... will this buyout impact your life they way you want it to? ...or will you be miserable or somehow transformed into someone you don't want to be as a result?