Re:Modafinil-Induced Changes in Functional Connectivity of H...
by api on Sunday April 09, 2017 @12:07AM
(#14070388)
The thing to do is threshold dose, don't increase the dose, and take holidays for long enough to allow recalibration. It's simple if you understand the control system mechanisms at work.
By threshold dose I mean take no more than is needed to get an effect. I experimented a bit and found 50-100mg of modafinil (1/4 to 1/2 pill) to be effective and have never taken 200mg.
Escalation on tolerance is the exact opposite of what you want. On the first hint of tolerance, stop. Again think about the control system at work. Your body is trying to maintain homeostasis, which is usually a very good thing.
By threshold dose I mean take no more than is needed to get an effect. I experimented a bit and found 50-100mg of modafinil (1/4 to 1/2 pill) to be effective and have never taken 200mg.
Escalation on tolerance is the exact opposite of what you want. On the first hint of tolerance, stop. Again think about the control system at work. Your body is trying to maintain homeostasis, which is usually a very good thing.