Modafinil-Induced Changes in Functional Connectivity of Healthy Elderly Subjects

Re:Modafinil-Induced Changes in Functional Connectivity of H... by always_good on Saturday April 08, 2017 @10:19PM (#14070128)

Well, I said "too quickly". You have to address tolerance for all drugs in this space, but some are ridiculous.

I couldn't even feel the Modafinil on day 3 without taking 5x the dose. That's a bit silly.

Instant release amphetamine ends up being more like a party drug for the same reason, though less extreme.

Compare that to a slow release amphetamine (prodrug) like Vyvanse where most people can hit a 2+ week cycle of constant use, or an indefinite cycle by only dosing a fraction of the week.

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Re:Modafinil-Induced Changes in Functional Connectivity of H... by krob on Sunday April 09, 2017 @08:59PM (#14075248)

if you follow what other people do when using modafinil, they sometimes mix coffee w/ small amounts of modafinil which improves it's overall offectiveness. I personally prefer the mental zing of Loose Leaf Black Tea.

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Re:Modafinil-Induced Changes in Functional Connectivity of H... by WalterSear on Monday April 10, 2017 @01:52PM (#14080909)

This won't help with tolerance.

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