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Re:Google App Engine: Datastore Performance Growing Pains by chasingsparks on Wednesday June 02, 2010 @09:04PM (#1400021)
I just started writing a GAE open-source community tool for rare disease orgs two weeks ago. I thought it was slow, but wrote it off as a limitation inherent to the Datastore. I moved a lot of things to the Memcache level, mitigating (mostly) the slow queries. That being said, I am glad it was actually a real problem.

I'm also impressed that they are not charging anyone until the problem is solved.

Re:Google App Engine: Datastore Performance Growing Pains by richardw on Thursday June 03, 2010 @03:13AM (#1400710)
GAE does have some performance surprises even during normal performance periods, so it's good that you're using Memcache etc now.

Couple other ideas:

Try to minimize read effort as much as possible, so e.g. pre-calculate as much as you can and rather optimize for performance than data cost. Data is cheap, so de-normalise where you need speed. Calc offline, so add a task to calculate something and return immediately to the user.